Bacteroides fragilis
Bacteroides fragilis is a topic covered in the Johns Hopkins ABX Guide.
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MICROBIOLOGY
- Small, pleomorphic Gram-negative anaerobic bacillus
- Of all species, B. fragilis causes most human Bacteroides infections.
- Other members of B. fragilis group include:
- Bacteroides distasonis
- Bacteroides ovatus
- Bacteroides thetaiotaomicron
- Bacteroides vulgatus
- Easily grown relative to other anaerobes
- Colonizes virtually all human colons
- Organism possibly important in the gut for immune modulation.
- B. fragilis group almost always susceptible to metronidazole, carbapenems, beta-lactam/beta-lactamase inhibitors
- Resistance rates to clindamycin, moxifloxacin, cefoxitin and cefotetan are increasing.
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MICROBIOLOGY
- Small, pleomorphic Gram-negative anaerobic bacillus
- Of all species, B. fragilis causes most human Bacteroides infections.
- Other members of B. fragilis group include:
- Bacteroides distasonis
- Bacteroides ovatus
- Bacteroides thetaiotaomicron
- Bacteroides vulgatus
- Easily grown relative to other anaerobes
- Colonizes virtually all human colons
- Organism possibly important in the gut for immune modulation.
- B. fragilis group almost always susceptible to metronidazole, carbapenems, beta-lactam/beta-lactamase inhibitors
- Resistance rates to clindamycin, moxifloxacin, cefoxitin and cefotetan are increasing.
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