Acne Vulgaris

Christopher J. Hoffmann, M.D., M.P.H.

PATHOGENS

Cutibacterium (ex. Propionibacterium) acnes (but not likely sole causative factor)
Pathogenesis: It is a primary inflammatory condition that involves: (1) abnormal follicular keratinization and occlusion; (2) excessive oil/sebum production; (3) bacterial superinfection (P. acnes); and (4) release of inflammatory mediators.

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