Do not confuse propylthiouracil with Purinethol (mercaptopurine).
Can be compounded by pharmacist into enema or suppository.
PO Administer at same time in relation to meals every day. Food may either increase or decrease absorption.
Instruct patient to take medication exactly as directed, around the clock. If a dose is missed, take as soon as remembered; take both doses together if almost time for next dose; check with health care professional if more than 1 dose is missed. Consult health care professional prior to discontinuing medication.
Instruct patient to monitor weight 2–3 times weekly. Report significant changes.
May cause drowsiness. Caution patient to avoid driving or other activities requiring alertness until response to medication is known.
Advise patient to consult health care professional regarding dietary sources of iodine (iodized salt, shellfish).
Advise patient to report sore throat, fever, chills, headache, malaise, weakness, yellowing of eyes or skin, unusual bleeding or bruising, symptoms of hyperthyroidism or hypothyroidism, or rash to health care professional promptly.
Advise patient to notify health care professional of all Rx or OTC medications, vitamins, or herbal products being taken and to consult with health care professional before taking other medications.
Advise patient to carry identification describing medication regimen at all times and to notify health care professional of medication regimen prior to treatment or surgery.
Advise female patient to notify health care professional if pregnancy is planned or suspected or if breast feeding.
Emphasize the importance of routine exams to monitor progress and to check for side effects.
Decrease in severity of symptoms of hyperthyroidism (lowered pulse rate and weight gain).
Return of thyroid function studies to normal.
May be used as short-term adjunctive therapy to prepare patient for thyroidectomy or radiation therapy or may be used in treatment of hyperthyroidism. Treatment of 6 mo to several yr may be necessary, usually averaging 1 yr.
propylthiouracil is a sample topic from the Davis's Drug Guide.
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