Administer adequate anesthesia and a broad–spectrum topical antimicrobial prior to injection.
Intravitreal Each vial is for single eye use only; discard after using.
Explain purpose of aflibercept to patient.
Advise patient to notify health care professional immediately if signs and symptoms of endophthalmitis or retinal detachment (eye pain, redness of eye, photophobia, blurring of vision) or hypersensitivity reactions (anaphylaxis, rash, pruritus, urticaria, or severe intraocular inflammation) occur.
May cause visual disturbances. Caution patient not to drive until visual function has sufficiently recovered.
Rep: Advise female patient of reproductive potential to use effective contraceptives prior to the initial dose, during treatment, and for at least 3 mo following completion of therapy and to notify health care provider if pregnancy is planned or suspected or if breast feeding.
Slowed progression of macular degeneration .
Decreased macular edema following CRVO.
Improved visual acuity in diabetic macular edema.
Decreased severity of diabetic retinopathy.
aflibercept is a sample topic from the Davis's Drug Guide.
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