Complementary/Alternative Medicine: This monograph describes a natural or herbal product that is not subject to FDA guidelines for medicines. Patients and clinicians are advised to read package labels carefully to ensure safe and efficacious use.
Peppermint reduces slow wave frequency in the small intestine, slows peristalsis and directly relaxes gastrointestinal smooth muscle. When applied topically, it has a direct inhibitory effect on sensitized pain receptors and may act centrally to alter pain perception.
Metabolism and Excretion: Unknown
Use Cautiously in:
Pregnancy and lactation when using medicinal amounts (above those amounts commonly found in foods).
Derm: contact dermatitis, flushing
GI: heartburn, nausea, vomiting, stomatitis
Misc: allergic reactions
* CAPITALS indicate life-threatening.
Underline indicate most frequent.
Natural Drug Interaction
PO (Adults): Dyspepsia– 1 mL of oil three times daily; Digestive disorders– 0.2–0.4 mL (1–2 enteric-coated capsules) three times daily; Tea– prepare with dried leaves/250 mL boiling water: 3–4 cups daily or 1.5–3 g peppermint oil/150 mL water: 1 cup three times daily.
Topical (Adults): Headache– 10% peppermint oil in ethanol solution apply to forehead and temples, repeat after 15 and 30 minutes.
Enteric-coated capsules: 0.2 mL oil/capsule
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