Complementary/Alternative Medicine: This monograph describes a natural or herbal product that is not subject to FDA guidelines for medicines. Patients and clinicians are advised to read package labels carefully to ensure safe and efficacious use.
Alcohol (↓ plasma lutein), cholestyramine and colestipol (↓ lutein absorption), CYP450-metabolized agents (alters enzyme activity), mineral oil (↓ lutein absorption), nicotine ↓ plasma lutein), retinol (↑ plasma lutein), may interact with agents with similar effects or related mechanisms of action ( antidiabetic, antilipemic, antioxidant, antineoplastic ), ↓ vitamin E levels.
Natural-Natural:
Concomitant administration with beta-carotene may reduce bioavailability of lutein.
Instruct patient to notify health care professional of all Rx or OTC medications, vitamins, or herbal products being taken and to consult with health care professional before taking other medications.
Advise female patient to notify health care professional if pregnancy is planned or suspected or if breastfeeding.