Complementary/Alternative Medicine: This monograph describes a natural or herbal product that is not subject to FDA guidelines for medicines. Patients and clinicians are advised to read package labels carefully to ensure safe and efficacious use. Pronunciation: loo-tee-in Trade Name(s) carotenoid xanthophyll zeaxanthin Ther. Class.
Prevention of lutein deficiency. Prevention of age-related macular degeneration (AMD), cataracts, and retinitis pigmentosa.
Lutein is a carotenoid with antioxidant properties that protect underlying ocular tissues from photodamage.
Decreased risk of development of AMD and cataracts.
Absorption: Unknown. Distribution: Unknown. Metabolism and Excretion: Unknown. Half-life: Unknown. TIME/ACTION PROFILE
ROUTE ONSET PEAK DURATION PO Unknown Unknown Unknown
Contraindicated in: Use Cautiously in:
Cystic fibrosis (decreased lutein absorption).
Adverse Reactions/Side Effects
CV: DISEASE Endo: carotendermia
CAPITALS indicate life-threatening. Underline indicate most frequent.
Natural Drug Interaction may cause ↓ lutein absorption. Orlistat (↓ plasma lutein), Alcohol and cholestyramine (↓ lutein absorption), colestipol CYP450-metabolized agents (alters enzyme activity), (↓ lutein absorption), mineral oil ↓ plasma lutein), nicotine retinol (↑ plasma lutein), may interact with agents with similar effects or related mechanisms of action ( , antidiabetic antilipemic, antioxidant, ), ↓ vitamin E levels. antineoplastic Natural-Natural:
Concomitant administration with beta-carotene may reduce bioavailability of lutein.
PO (Adults) : 6–20 mg/day.
Softgels: 6 mg, 20 mg
Obtain ophthalmic examinations at least yearly during therapy.
PO Administer capsules once daily.
Instruct patient to take as directed. Instruct patient to notify health care professional of all Rx or OTC medications, vitamins, or herbal products being taken and to consult with health care professional before taking other medications. Advise female patient to notify health care professional if pregnancy is planned or suspected or if breastfeeding.
Decrease in risk or cataracts and age-related macular degeneration.
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