Polyarteritis Nodosa

Basics

Description

An inflammatory process of small- and medium-sized muscular arteries resulting in multi-system organ dysfunction

Epidemiology

Incidence

Extremely rare in childhood

Prevalence

Prevalence equal in boys and girls

Pathophysiology

Necrotizing arteritis of small- and medium-sized arteries resulting in segmental fibrinoid necrosis

Etiology

  • Idiopathic
  • Postinfectious (streptococcal, especially for isolated cutaneous form)
  • Hepatitis B association rare in children with widespread vaccination

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